Radiation Protection
- Patient dosimetry
- Radiation safety
- Waste management
About NRG PALLAS
NRG PALLAS brings together more than 60 years of nuclear engineering, research, and 24/7 operational reactor experience for one unique goal: the safe, reliable, and efficient use of nuclear technology. Our qualified engineers and consultants provide services and solutions in the fields of nuclear safety, maintenance, decommissioning and waste processing, as well as radiation safety.
NRG PALLAS operates independently of other service providers and regulatory bodies. In Petten, North Holland, we have a unique nuclear infrastructure (High Flux Reactor, hot cells, radiochemical laboratories, decontamination and waste processing facilities), and in Arnhem, we have a testing hall for inspections.
- Development of advanced dosimetry models
- Improve dosimetry of radionuclide therapy
- Treatment optimisation
- Compliance to radiation safety
- Protection of patients, professionals and healthcare providers
- Protection of the public and the environment
- Minimise radioactive waste
- Recycling and re-use of radioactive resources
- Innovative mining of rawmaterials
Compliance: providing support on radiation protection compliance for the PALLAS-reactor and FIELD-LAB
- Preparing the license application for the new PALLAS-reactor
- Design reviews
- Reviewing the probabilistic safety assessment report (PSAR)
- Writing the Safety Report
- Support in setting up the radiation protection organization
PBPK modelling: development of a physiologically based pharma-cokinetic modelling (PBPK)
- Development of a PBPK model parameterised for Lu-177-DOTATATE and Pb-212-DOTAMTATE
- Simulation of the compound in the organs (e.g. liver, spleen, kidney) and the tumour at the different sub-tissue levels.
- Improved understanding on the behaviour of novel radiopharmaceuticals
Dosimetry modelling: benchmark of tumor dose in brachy-therapy using alternative isotopes
- Development of a dosimetry model
- Computation of the absorded dose in the surrounding tumor tissue using different activities of iridium-192, ytterbium-169 and thulium-170
- Guidance on the minimum required specific activity for new isotopes
Product optimisation: assessment on the impact of isotope impurities on the patient dose
- Characterisation of the radionuclide purificate
- Performing a PBPK and dosimetry modelling on the isotope impurities
- Making recommendations for possible requirements on product purity
Partners & clients around the world
Radiation Safety
Is your organisation compliant with radiation safety regulation? Do you have challenges to handle your radioactive waste? Do you have to demonstrate and optimise the full radiation impact of your innovations or new-build activities? NRG PALLAS has all the expertise, tools and infrastructure to help you with any issues on radiation safety.
Dosimetry
Do you need a partner to help with the early assessment of radiopharmaceutical uptake and dosimetry? Do you want to benchmark specific innovations in your radiopharmaceutical, choice of isotope or search for options in treatment optimisation? NRG PALLAS has developed state-of-the-art software to simulate the uptake of radiopharmaceuticals and assess the dosimetry to organs and tumor tissue. NRG PALLAS is your partner in research.